Protein Name proteolipid protein (myelin) 1
Organism Mus musculus
Gene ID 18823
Gene Symbol


UniProt P60202 (MYPR_MOUSE), Q3UYM8 (Q3UYM8_MOUSE)
Relationships Total Number of functionally related compound(s) : 161
Total Number of Articles : 154

proteolipid protein (myelin) 1

Gene Summary

Predicted to enable identical protein binding activity. Predicted to be a structural constituent of myelin sheath. Involved in positive regulation of gene expression. Acts upstream of or within several processes, including cell maturation; long-chain fatty acid biosynthetic process; and neurogenesis. Located in myelin sheath. Is expressed in several structures, including alimentary system; cardiovascular system; musculature; nervous system; and sensory organ. Used to study Pelizaeus-Merzbacher disease and hereditary spastic paraplegia 2. Human ortholog(s) of this gene implicated in Pelizaeus-Merzbacher disease and hereditary spastic paraplegia 2. Orthologous to human PLP1 (proteolipid protein 1). [provided by Alliance of Genome Resources, Apr 2022]

  • myelin proteolipid protein
  • lipophilin
  • myelin synthesis deficiency
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