| Protein Name | proteolipid protein (myelin) 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 18823 |
| Gene Symbol | Plp1 |
| UniProt | P60202 (MYPR_MOUSE), Q3UYM8 (Q3UYM8_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
161
Total Number of Articles : 154 |
Description |
proteolipid protein (myelin) 1 |
| Gene Summary |
Predicted to enable identical protein binding activity. Predicted to be a structural constituent of myelin sheath. Involved in positive regulation of gene expression. Acts upstream of or within inflammatory response; long-chain fatty acid biosynthetic process; and neurogenesis. Located in myelin sheath. Is expressed in several structures, including alimentary system; integumental system; musculature; nervous system; and sensory organ. Used to study Pelizaeus-Merzbacher disease and hereditary spastic paraplegia 2. Human ortholog(s) of this gene implicated in Pelizaeus-Merzbacher disease and hereditary spastic paraplegia 2. Orthologous to human PLP1 (proteolipid protein 1). [provided by Alliance of Genome Resources, Jun 2025] |
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