| Protein Name | IQ motif and Sec7 domain 1 |
|---|---|
| Organism | Mus musculus |
| Gene ID | 232227 |
| Gene Symbol | Iqsec1 |
| UniProt | Q8R0S2 (IQEC1_MOUSE), A0A1D5RM83 (A0A1D5RM83_MOUSE), E9PUA3 (E9PUA3_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
5
Total Number of Articles : 4 |
Description |
IQ motif and Sec7 domain 1 |
| Gene Summary |
Enables protein kinase binding activity. Involved in several processes, including positive regulation of focal adhesion disassembly; positive regulation of keratinocyte migration; and regulation of postsynaptic neurotransmitter receptor internalization. Is active in Schaffer collateral - CA1 synapse; glutamatergic synapse; and postsynaptic density, intracellular component. Is expressed in central nervous system; forelimb muscle; sensory organ; and viscerocranium. Human ortholog(s) of this gene implicated in intellectual developmental disorder with short stature and behavioral abnormalities and lung adenocarcinoma. Orthologous to human IQSEC1 (IQ motif and Sec7 domain ArfGEF 1). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |