| Protein Name | deoxyribonuclease I |
|---|---|
| Organism | Mus musculus |
| Gene ID | 13419 |
| Gene Symbol | Dnase1 |
| UniProt | P49183 (DNAS1_MOUSE), Q14BW6 (Q14BW6_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
126
Total Number of Articles : 124 |
Description |
deoxyribonuclease I |
| Gene Summary |
Enables deoxyribonuclease I activity. Involved in several processes, including DNA catabolic process; neutrophil activation involved in immune response; and regulation of neutrophil mediated cytotoxicity. Predicted to be located in extracellular region; nuclear envelope; and zymogen granule. Predicted to be active in nucleus. Is expressed in jejunum; metanephros; and tongue. Used to study systemic lupus erythematosus. Human ortholog(s) of this gene implicated in systemic lupus erythematosus. Orthologous to human DNASE1 (deoxyribonuclease 1). [provided by Alliance of Genome Resources, Apr 2025] |
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