Protein Name secreted acidic cysteine rich glycoprotein
Organism Mus musculus
Gene ID 20692
Gene Symbol

Sparc

UniProt P07214 (SPRC_MOUSE), Q5NCU5 (Q5NCU5_MOUSE), Q5NCU4 (Q5NCU4_MOUSE)
Relationships Total Number of functionally related compound(s) : 121
Total Number of Articles : 130
Description

secreted acidic cysteine rich glycoprotein

Gene Summary

Enables calcium ion binding activity and extracellular matrix binding activity. Acts upstream of or within several processes, including bone development; cellular response to growth factor stimulus; and pigmentation. Located in extracellular matrix and extracellular space. Is expressed in several structures, including brain; egg cylinder; genitourinary system; jaw; and sensory organ. Human ortholog(s) of this gene implicated in cervix carcinoma; endometrial carcinoma; multiple myeloma; and osteogenesis imperfecta type 17. Orthologous to human SPARC (secreted protein acidic and cysteine rich). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • SPARC
  • basement-membrane protein 40
  • osteonectin
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Properties