Protein Name potassium voltage-gated channel, Isk-related subfamily, gene 2
Organism Mus musculus
Gene ID 246133
Gene Symbol

Kcne2

UniProt Q9D808 (KCNE2_MOUSE), A0A0R4J1J2 (A0A0R4J1J2_MOUSE)
Relationships Total Number of functionally related compound(s) : 16
Total Number of Articles : 10
Description

potassium voltage-gated channel, Isk-related subfamily, gene 2

Gene Summary

Predicted to enable several functions, including identical protein binding activity; transmembrane transporter binding activity; and voltage-gated potassium channel activity. Predicted to contribute to delayed rectifier potassium channel activity; inward rectifier potassium channel activity; and voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization. Involved in iodide transport; multicellular organismal response to stress; and myo-inositol transport. Acts upstream of or within several processes, including potassium ion transmembrane transport; regulation of ventricular cardiac muscle cell membrane repolarization; and ventricular cardiac muscle cell action potential. Located in apical plasma membrane. Part of voltage-gated potassium channel complex. Is expressed in several structures, including alimentary system; heart; nervous system; sensory organ; and skeleton. Human ortholog(s) of this gene implicated in atrial fibrillation; familial atrial fibrillation; long QT syndrome; and long QT syndrome 6. Orthologous to human KCNE2 (potassium voltage-gated channel subfamily E regulatory subunit 2). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • potassium voltage-gated channel subfamily E member 2
  • minK-related peptide 1
  • minimum potassium ion channel related peptide 1
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Properties