Protein Name glucosaminyl (N-acetyl) transferase 1, core 2
Organism Mus musculus
Gene ID 14537
Gene Symbol

Gcnt1

UniProt Q09324 (GCNT1_MOUSE)
Relationships Total Number of functionally related compound(s) : 19
Total Number of Articles : 17
Description

glucosaminyl (N-acetyl) transferase 1, core 2

Gene Summary

Enables beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase activity. Involved in core 2 O-glycan biosynthetic process and positive regulation of leukocyte tethering or rolling. Acts upstream of or within kidney morphogenesis and tissue morphogenesis. Predicted to be located in Golgi cisterna; extracellular space; and trans-Golgi network. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; sensory organ; and skeleton. Orthologous to human GCNT1 (glucosaminyl (N-acetyl) transferase 1). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase
  • beta-1,3-galactosyl-O-glycosyl-glycoprotein beta-1,6-N-acetylglucosaminyltransferase (Core 2 branching enzyme) (Core2-GlcNAc-transferase) (C2GNT)
  • core 2 beta-1,6-N-acetylglucosaminyltransferase
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Properties