Protein Name FTO alpha-ketoglutarate dependent dioxygenase
Organism Mus musculus
Gene ID 26383
Gene Symbol

Fto

UniProt Q8BGW1 (FTO_MOUSE)
Relationships Total Number of functionally related compound(s) : 65
Total Number of Articles : 62
Description

FTO alpha-ketoglutarate dependent dioxygenase

Gene Summary

Enables DNA-N1-methyladenine dioxygenase activity; oxidative DNA demethylase activity; and oxidative RNA demethylase activity. Involved in several processes, including nucleic acid metabolic process; regulation of respiratory system process; and regulation of white fat cell proliferation. Located in nucleus. Is expressed in several structures, including gonad; hemolymphoid system gland; liver; lung; and salivary gland. Human ortholog(s) of this gene implicated in obesity. Orthologous to human FTO (FTO alpha-ketoglutarate dependent dioxygenase). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • alpha-ketoglutarate-dependent dioxygenase FTO
  • U6 small nuclear RNA (2'-O-methyladenosine-N(6)-)-demethylase FTO
  • U6 small nuclear RNA N(6)-methyladenosine-demethylase FTO
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Properties