| Protein Name | ftz transcription factor 1 |
|---|---|
| Organism | Drosophila melanogaster |
| Gene ID | 40045 |
| Gene Symbol | ftz-f1 |
| UniProt | P33244 (FTZF1_DROME), M9NFK2 (M9NFK2_DROME), A0A0S0WH29 (A0A0S0WH29_DROME) |
| Relationships |
Total Number of functionally related compound(s) :
13
Total Number of Articles : 27 |
Description |
ftz transcription factor 1 |
| Gene Summary |
Enables DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II-specific DNA-binding transcription factor binding activity; and transcription cis-regulatory region binding activity. Involved in several processes, including instar larval or pupal development; juvenile hormone mediated signaling pathway; and nervous system development. Located in nucleus. Is expressed in several structures, including appendage; follicle cell; gland; gut section; and ring gland. Human ortholog(s) of this gene implicated in 46,XX sex reversal 4; 46,XY sex reversal 3; Zellweger syndrome; primary ovarian insufficiency 7; and spermatogenic failure 8. Orthologous to several human genes including NR5A1 (nuclear receptor subfamily 5 group A member 1). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |