Protein Name surfactant protein A1
Organism Rattus norvegicus
Gene ID 24773
Gene Symbol

Sftpa1

UniProt P08427 (SFTPA_RAT)
Relationships Total Number of functionally related compound(s) : 239
Total Number of Articles : 205
Description

surfactant protein A1

Gene Summary

Predicted to enable carbohydrate binding activity and metal ion binding activity. Involved in several processes, including cellular response to mechanical stimulus; cellular response to nitric oxide; and response to vitamin A. Located in extracellular space; multivesicular body; and rough endoplasmic reticulum. Biomarker of asthma; bacterial pneumonia; lung disease; newborn respiratory distress syndrome; and obesity. Human ortholog(s) of this gene implicated in lung disease (multiple) and respiratory syncytial virus infectious disease. Orthologous to several human genes including SFTPA1 (surfactant protein A1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • pulmonary surfactant-associated protein A
  • Surfactant-associated protein 1 (pulmonary surfactant protein, SP-A)
  • pulmonary surfactant-associated protein A-like
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Properties