Protein Name serpin family A member 3
Organism Homo sapiens
Gene ID 12
Gene Symbol


UniProt P01011 (AACT_HUMAN), A0A024R6P0 (A0A024R6P0_HUMAN)
Relationships Total Number of functionally related compound(s) : 120
Total Number of Articles : 146

serpin family A member 3

Gene Summary

The protein encoded by this gene is a member of the serpin family of proteins, a group of proteins that inhibit serine proteases. This gene is one in a cluster of serpin genes located on the q arm of chromosome 14. Polymorphisms in this protein appear to be tissue specific and influence protease targeting. Variations in this protein's sequence have been implicated in Alzheimer's disease, and deficiency of this protein has been associated with liver disease. Mutations have been identified in patients with Parkinson disease and chronic obstructive pulmonary disease. [provided by RefSeq, Jun 2020]

  • alpha-1-antichymotrypsin
  • cell growth-inhibiting gene 24/25 protein
  • growth-inhibiting protein 24
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