CPRiL

Npr2

natriuretic peptide receptor 2

Enables guanylate cyclase activity; identical protein binding activity; and natriuretic peptide receptor activity. Involved in several processes, including reproductive structure development; skeletal system development; and vasculature development. Acts upstream of or within bone development; negative regulation of meiotic cell cycle; and negative regulation of oocyte maturation. Is active in several cellular components, including cilium; neuron projection; and nucleus. Is expressed in several structures, including alimentary system; genitourinary system; nervous system; sensory organ; and skeleton. Used to study achondroplasia; acromesomelic dysplasia, Maroteaux type; and bone development disease. Human ortholog(s) of this gene implicated in Miura type epiphyseal chondrodysplasia; acromesomelic dysplasia, Maroteaux type; and essential hypertension. Orthologous to human NPR2 (natriuretic peptide receptor 2). [provided by Alliance of Genome Resources, Jul 2025]

• atrial natriuretic peptide receptor 2
• ANP-B
• ANPR-B
NPR-B
Nppb receptor
atrial natriuretic peptide receptor type B
guanylate cyclase B
guanylyl cyclase-B
natriuretic peptide receptor B type
GC-B
GC-B2
GC-B3
cn
mNPR-B
pwe