Protein Name CD8 subunit alpha
Organism Mus musculus
Gene ID 12525
Gene Symbol

Cd8a

UniProt P01731 (CD8A_MOUSE), Q8CAX3 (Q8CAX3_MOUSE)
Relationships Total Number of functionally related compound(s) : 183
Total Number of Articles : 225
Description

CD8 subunit alpha

Gene Summary

Enables identical protein binding activity. Acts upstream of or within several processes, including cytotoxic T cell differentiation; defense response to virus; and positive regulation of calcium-mediated signaling. Located in external side of plasma membrane. Is expressed in several structures, including endocrine gland; exocrine gland; genitourinary system; gut; and hemolymphoid system gland. Orthologous to human CD8A (CD8a molecule). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • T-cell surface glycoprotein CD8 alpha chain
  • CD8 antigen, alpha chain
  • Lyt-2.1 lymphocyte differentiation antigen (AA at 100)
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Properties