Protein Name malic enzyme 1
Organism Homo sapiens
Gene ID 4199
Gene Symbol

ME1

UniProt P48163 (MAOX_HUMAN)
Relationships Total Number of functionally related compound(s) : 271
Total Number of Articles : 284
Description

malic enzyme 1

Gene Summary

This gene encodes a cytosolic, NADP-dependent enzyme that generates NADPH for fatty acid biosynthesis. The activity of this enzyme, the reversible oxidative decarboxylation of malate, links the glycolytic and citric acid cycles. The regulation of expression for this gene is complex. Increased expression can result from elevated levels of thyroid hormones or by higher proportions of carbohydrates in the diet. [provided by RefSeq, Jul 2008]

synonyms
  • NADP-dependent malic enzyme
  • Malic enzyme, cytoplasmic
  • NADP-ME
Click to show/hide the synonyms
Properties