Protein Name low density lipoprotein receptor-related protein 2
Organism Mus musculus
Gene ID 14725
Gene Symbol


Relationships Total Number of functionally related compound(s) : 86
Total Number of Articles : 83

low density lipoprotein receptor-related protein 2

Gene Summary

Predicted to enable several functions, including PDZ domain binding activity; chaperone binding activity; and insulin-like growth factor I binding activity. Involved in several processes, including circulatory system development; nervous system development; and reproductive structure development. Acts upstream of or within several processes, including animal organ development; circulatory system development; and vitamin metabolic process. Located in several cellular components, including brush border membrane; clathrin-coated pit; and cytoplasmic vesicle. Is expressed in several structures, including egg cylinder; heart and pericardium; metanephros; ureter; and ventricular layer. Used to study Donnai-Barrow syndrome; Fanconi syndrome; and degenerative myopia. Human ortholog(s) of this gene implicated in Donnai-Barrow syndrome and autoimmune thyroiditis. Orthologous to human LRP2 (LDL receptor related protein 2). [provided by Alliance of Genome Resources, Apr 2022]

  • low-density lipoprotein receptor-related protein 2
  • glycoprotein 330
  • D230004K18Rik
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