Protein Name dishevelled segment polarity protein 2
Organism Homo sapiens
Gene ID 1856
Gene Symbol

DVL2

UniProt O14641 (DVL2_HUMAN)
Relationships Total Number of functionally related compound(s) : 36
Total Number of Articles : 37
Description

dishevelled segment polarity protein 2

Gene Summary

This gene encodes a member of the dishevelled (dsh) protein family. The vertebrate dsh proteins have approximately 40% amino acid sequence similarity with Drosophila dsh. This gene encodes a 90-kD protein that undergoes posttranslational phosphorylation to form a 95-kD cytoplasmic protein, which may play a role in the signal transduction pathway mediated by multiple Wnt proteins. The mechanisms of dishevelled function in Wnt signaling are likely to be conserved among metazoans. [provided by RefSeq, Jul 2008]

synonyms
  • segment polarity protein dishevelled homolog DVL-2
  • dishevelled 2 (homologous to Drosophila dsh)
  • dishevelled, dsh homolog 2
Click to show/hide the synonyms
Properties