Protein Name CD1c molecule
Organism Homo sapiens
Gene ID 911
Gene Symbol

CD1C

UniProt P29017 (CD1C_HUMAN)
Relationships Total Number of functionally related compound(s) : 272
Total Number of Articles : 301
Description

CD1c molecule

Gene Summary

This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene is broadly distributed throughout the endocytic system via a tyrosine-based motif in the cytoplasmic tail. Alternatively spliced transcript variants of this gene have been observed, but their full-length nature is not known. [provided by RefSeq, Jul 2008]

synonyms
  • T-cell surface glycoprotein CD1c
  • CD1C antigen, c polypeptide
  • cortical thymocyte antigen CD1C
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Properties