Protein Name luteinizing hormone/choriogonadotropin receptor
Organism Rattus norvegicus
Gene ID 25477
Gene Symbol

Lhcgr

UniProt P16235 (LSHR_RAT)
Relationships Total Number of functionally related compound(s) : 166
Total Number of Articles : 217
Description

luteinizing hormone/choriogonadotropin receptor

Gene Summary

Enables several functions, including ATPase binding activity; identical protein binding activity; and peptide hormone binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; activation of adenylate cyclase activity; and arachidonic acid secretion. Located in several cellular components, including endoplasmic reticulum; endosome; and lysosome. Is integral component of plasma membrane and intrinsic component of external side of plasma membrane. Part of receptor complex. Human ortholog(s) of this gene implicated in Leydig cell hypoplasia; Leydig cell tumor; breast cancer; familial male-limited precocious puberty; and gonadal disease. Orthologous to human LHCGR (luteinizing hormone/choriogonadotropin receptor). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • lutropin-choriogonadotropic hormone receptor
  • LH receptor
  • LH/CG receptor
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Properties