| Protein Name | nuclear factor of activated T-cells 1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 100361818 |
| Gene Symbol | Nfatc1 |
| UniProt | - |
| Relationships |
Total Number of functionally related compound(s) :
57
Total Number of Articles : 59 |
Description |
nuclear factor of activated T-cells 1 |
| Gene Summary |
Enables RNA polymerase II transcription regulatory region sequence-specific DNA binding activity and transcription coactivator binding activity. Involved in several processes, including cellular response to transforming growth factor beta stimulus; cellular response to tumor necrosis factor; and positive regulation of nucleobase-containing compound metabolic process. Located in nucleus; perinuclear region of cytoplasm; and sarcoplasm. Biomarker of kidney disease and osteoarthritis. Human ortholog(s) of this gene implicated in congenital heart disease and ventricular septal defect. Orthologous to human NFATC1 (nuclear factor of activated T cells 1). [provided by Alliance of Genome Resources, Jul 2025] |
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