Protein Name bleomycin hydrolase
Organism Homo sapiens
Gene ID 642
Gene Symbol

BLMH

UniProt Q13867 (BLMH_HUMAN)
Relationships Total Number of functionally related compound(s) : 134
Total Number of Articles : 76
Description

bleomycin hydrolase

Gene Summary

Bleomycin hydrolase (BMH) is a cytoplasmic cysteine peptidase that is highly conserved through evolution; however, the only known activity of the enzyme is metabolic inactivation of the glycopeptide bleomycin (BLM), an essential component of combination chemotherapy regimens for cancer. The protein contains the signature active site residues of the cysteine protease papain superfamily. [provided by RefSeq, Jul 2008]

synonyms
  • bleomycin hydrolase
  • BLM hydrolase
  • BH
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Properties