Protein Name N-acylsphingosine amidohydrolase 2
Organism Rattus norvegicus
Gene ID 114104
Gene Symbol

Asah2

UniProt Q91XT9 (ASAH2_RAT)
Relationships Total Number of functionally related compound(s) : 24
Total Number of Articles : 18
Description

N-acylsphingosine amidohydrolase 2

Gene Summary

Enables dihydroceramidase activity and phytoceramidase activity. Involved in response to organic substance and sphingolipid metabolic process. Located in extracellular space; mitochondrion; and plasma membrane. Is integral component of plasma membrane. Colocalizes with membrane raft. Orthologous to several human genes including ASAH2B (N-acylsphingosine amidohydrolase 2B). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • neutral ceramidase
  • N-acylsphingosine amidohydrolase (non-lysosomal ceramidase) 2
  • NCDase
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Properties