Protein Name Rap guanine nucleotide exchange factor (GEF) 1
Organism Mus musculus
Gene ID 107746
Gene Symbol

Rapgef1

UniProt Q91ZZ2 (Q91ZZ2_MOUSE), Q3UGX8 (Q3UGX8_MOUSE), Q3UHC1 (Q3UHC1_MOUSE), A0A5F8MPI9 (A0A5F8MPI9_MOUSE), Q8C5V7 (Q8C5V7_MOUSE)
Relationships Total Number of functionally related compound(s) : 70
Total Number of Articles : 74
Description

Rap guanine nucleotide exchange factor (GEF) 1

Gene Summary

Enables guanyl-nucleotide exchange factor activity. Acts upstream of or within several processes, including activation of GTPase activity; negative regulation of signal transduction; and platelet-derived growth factor receptor signaling pathway. Located in cytoplasm and nucleus. Is expressed in several structures, including alimentary system; brain; cardiovascular system; genitourinary system; and immune system. Orthologous to human RAPGEF1 (Rap guanine nucleotide exchange factor 1). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • rap guanine nucleotide exchange factor 1
  • guanine nucleotide releasing factor 2
  • 4932418O06Rik
Click to show/hide the synonyms
Properties