| Protein Name | sel-1 suppressor of lin-12-like (C. elegans) |
|---|---|
| Organism | Mus musculus |
| Gene ID | 20338 |
| Gene Symbol | Sel1l |
| UniProt | Q9Z2G6 (SE1L1_MOUSE), Q6GTY4 (Q6GTY4_MOUSE), Q5DTL8 (Q5DTL8_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
6
Total Number of Articles : 5 |
Description |
sel-1 suppressor of lin-12-like (C. elegans) |
| Gene Summary |
Involved in ERAD pathway; protein secretion; and triglyceride metabolic process. Acts upstream of or within response to endoplasmic reticulum stress. Predicted to be located in endoplasmic reticulum. Predicted to be part of Derlin-1 retrotranslocation complex and Hrd1p ubiquitin ligase ERAD-L complex. Predicted to be active in endoplasmic reticulum membrane. Is expressed in several structures, including genitourinary system; liver; neural tube; pancreas; and spleen. Human ortholog(s) of this gene implicated in pancreatic cancer. Orthologous to human SEL1L (SEL1L adaptor subunit of SYVN1 ubiquitin ligase). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |