Protein Name caspase recruitment domain family, member 14
Organism Mus musculus
Gene ID 170720
Gene Symbol

Card14

UniProt Q99KF0 (CAR14_MOUSE)
Relationships Total Number of functionally related compound(s) : 2
Total Number of Articles : 3
Description

caspase recruitment domain family, member 14

Gene Summary

Predicted to enable CARD domain binding activity. Predicted to be involved in several processes, including positive regulation of NF-kappaB transcription factor activity; positive regulation of canonical NF-kappaB signal transduction; and tumor necrosis factor-mediated signaling pathway. Predicted to be located in aggresome and cytosol. Is expressed in gut; nose; and vibrissa. Used to study pityriasis rubra pilaris and psoriasis 2. Human ortholog(s) of this gene implicated in pityriasis rubra pilaris and psoriasis 2. Orthologous to human CARD14 (caspase recruitment domain family member 14). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • caspase recruitment domain-containing protein 14
  • bcl10-interacting MAGUK protein 2
  • Bimp2
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Properties