Protein Name endogenous retrovirus group V member 2 Env polyprotein
Organism Macaca mulatta
Gene ID 100429036
Gene Symbol

ERVV-2

UniProt -
Relationships Total Number of functionally related compound(s) : 5
Total Number of Articles : 5
Description

endogenous retrovirus group V member 2, envelope

Gene Summary

Many different human endogenous retrovirus (HERV) families are expressed in normal placental tissue at high levels, suggesting that HERVs are functionally important in reproduction. This gene is part of an HERV provirus on chromosome 19 that has inactivating mutations in the gag and pol genes. This envelope glycoprotein gene appears to have been selectively preserved. The gene's protein product is expressed in the placenta and acts as a syncytin in Old World monkeys, but has lost the fusogenic activity in humans and other primate lineages. [provided by RefSeq, Jun 2015]

synonyms
  • endogenous retrovirus group V member 2 Env polyprotein
  • envelope glycoprotein
  • envelope protein ENVV2
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Properties