Protein Name 5-hydroxytryptamine (serotonin) receptor 3A
Organism Mus musculus
Gene ID 15561
Gene Symbol

Htr3a

UniProt P23979 (5HT3A_MOUSE), Q8K1F4 (Q8K1F4_MOUSE), E9QLC0 (E9QLC0_MOUSE)
Relationships Total Number of functionally related compound(s) : 78
Total Number of Articles : 61
Description

5-hydroxytryptamine (serotonin) receptor 3A

Gene Summary

Enables identical protein binding activity. Predicted to be involved in several processes, including chemical synaptic transmission; positive regulation of ion transmembrane transporter activity; and regulation of membrane potential. Predicted to act upstream of or within ion transport. Predicted to be located in several cellular components, including axon; cleavage furrow; and neuronal cell body. Predicted to be part of serotonin-activated cation-selective channel complex. Predicted to be active in neuron projection and synapse. Predicted to be integral component of plasma membrane. Is expressed in several structures, including central nervous system; eye; gallbladder; genitourinary system; and gut. Human ortholog(s) of this gene implicated in irritable bowel syndrome. Orthologous to human HTR3A (5-hydroxytryptamine receptor 3A). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • 5-hydroxytryptamine receptor 3A
  • 5-hydroxytryptamine receptor 3
  • 5HT3 serotonin receptor
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Properties