| Protein Name | lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase) |
|---|---|
| Organism | Mus musculus |
| Gene ID | 79235 |
| Gene Symbol | Lrat |
| UniProt | Q9JI60 (LRAT_MOUSE), B2RUR5 (B2RUR5_MOUSE) |
| Relationships |
Total Number of functionally related compound(s) :
33
Total Number of Articles : 49 |
Description |
lecithin-retinol acyltransferase (phosphatidylcholine-retinol-O-acyltransferase) |
| Gene Summary |
Enables O-palmitoyltransferase activity and phosphatidylcholine-retinol O-acyltransferase activity. Involved in lipid storage and retinol metabolic process. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; positive regulation of lipid transport; and vitamin A metabolic process. Located in endoplasmic reticulum. Is expressed in several structures, including extraembryonic component; gut; midbrain; reproductive system; and retina. Used to study Leber congenital amaurosis 14. Human ortholog(s) of this gene implicated in Leber congenital amaurosis 14 and retinitis pigmentosa. Orthologous to human LRAT (lecithin retinol acyltransferase). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |