Protein Name adrenergic receptor, beta 2
Organism Mus musculus
Gene ID 11555
Gene Symbol

Adrb2

UniProt P18762 (ADRB2_MOUSE)
Relationships Total Number of functionally related compound(s) : 205
Total Number of Articles : 394
Description

adrenergic receptor, beta 2

Gene Summary

This intronless gene belongs to the G-protein-coupled receptor superfamily, which includes transmembrane proteins that play a role in signal transduction across biological membranes resulting in a variety of physiological responses. The encoded protein is a beta-2 adrenergic receptor which is activated by catecholamine ligands such as adrenaline and epinephrine. The protein participates in the classical signaling pathway involving G protein, adenylyl cyclase, cAMP (3'-5'-cyclic adenosine monophosphate) and protein kinase A (PKA). In humans, this gene is implicated in susceptibility to nocturnal asthma, obesity and type 2 diabetes. [provided by RefSeq, Apr 2013]

synonyms
  • beta-2 adrenergic receptor
  • beta 2-AR
  • beta-2 adrenoceptor
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Properties