Protein Name wingless-type MMTV integration site family, member 3
Organism Mus musculus
Gene ID 22415
Gene Symbol

Wnt3

UniProt P17553 (WNT3_MOUSE), A2A649 (A2A649_MOUSE), Q3TQ59 (Q3TQ59_MOUSE)
Relationships Total Number of functionally related compound(s) : 23
Total Number of Articles : 19
Description

wingless-type MMTV integration site family, member 3

Gene Summary

Enables protein domain specific binding activity. Involved in positive regulation of Wnt signaling pathway. Acts upstream of or within several processes, including axis specification; embryonic morphogenesis; and generation of neurons. Located in extracellular matrix. Is expressed in several structures, including alimentary system; branchial arch; central nervous system; embryo ectoderm; and genitourinary system. Human ortholog(s) of this gene implicated in tetraamelia syndrome 1. Orthologous to human WNT3 (Wnt family member 3). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • proto-oncogene Wnt-3
  • proto-oncogene Int-4
  • proto-oncogene protein Wnt-3
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Properties