Protein Name folate receptor alpha
Organism Mus musculus
Gene ID 14275
Gene Symbol

Folr1

UniProt P35846 (FOLR1_MOUSE)
Relationships Total Number of functionally related compound(s) : 25
Total Number of Articles : 40
Description

folate receptor alpha

Gene Summary

Predicted to enable carboxylic acid binding activity; folic acid receptor activity; and signaling receptor activity. Involved in circulatory system development; nervous system development; and regulation of signal transduction. Acts upstream of or within folic acid metabolic process. Predicted to be located in several cellular components, including apical plasma membrane; basolateral plasma membrane; and brush border membrane. Predicted to be anchored component of plasma membrane. Predicted to be anchored component of external side of plasma membrane. Is expressed in several structures, including brain; early conceptus; genitourinary system; gut; and retina. Human ortholog(s) of this gene implicated in cerebral folate receptor alpha deficiency. Orthologous to human FOLR1 (folate receptor alpha). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • folate receptor alpha
  • FR-alpha
  • folate receptor 1 (adult)
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Properties