Protein Name solute carrier family 25 member 5
Organism Homo sapiens
Gene ID 292
Gene Symbol


UniProt P05141 (ADT2_HUMAN), Q6NVC0 (Q6NVC0_HUMAN)
Relationships Total Number of functionally related compound(s) : 195
Total Number of Articles : 217

solute carrier family 25 member 5

Gene Summary

This gene is a member of the mitochondrial carrier subfamily of solute carrier protein genes. The product of this gene functions as a gated pore that translocates ADP from the cytoplasm into the mitochondrial matrix and ATP from the mitochondrial matrix into the cytoplasm. The protein forms a homodimer embedded in the inner mitochondria membrane. Suppressed expression of this gene has been shown to induce apoptosis and inhibit tumor growth. The human genome contains several non-transcribed pseudogenes of this gene.[provided by RefSeq, Jun 2013]

  • ADP/ATP translocase 2
  • adenine nucleotide translocator 2 (fibroblast)
  • solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5
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