| Protein Name | anaphase promoting complex subunit 7 |
|---|---|
| Organism | Homo sapiens |
| Gene ID | 51434 |
| Gene Symbol | ANAPC7 |
| UniProt | Q9UJX3 (APC7_HUMAN), A0A024RBJ3 (A0A024RBJ3_HUMAN), Q4KMX6 (Q4KMX6_HUMAN), Q69YV3 (Q69YV3_HUMAN) |
| Relationships |
Total Number of functionally related compound(s) :
4
Total Number of Articles : 4 |
Description |
anaphase promoting complex subunit 7 |
| Gene Summary |
This gene encodes a tetratricopeptide repeat containing component of the anaphase promoting complex/cyclosome (APC/C), a large E3 ubiquitin ligase that controls cell cycle progression by targeting a number of cell cycle regulators such as B-type cyclins for 26S proteasome-mediated degradation through ubiquitination. The encoded protein is required for proper protein ubiquitination function of APC/C and for the interaction of APC/C with certain transcription coactivators. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2008] |
| synonyms |
|
| Properties | |