Protein Name islet amyloid polypeptide
Organism Rattus norvegicus
Gene ID 24476
Gene Symbol

Iapp

UniProt P12969 (IAPP_RAT)
Relationships Total Number of functionally related compound(s) : 251
Total Number of Articles : 325
Description

islet amyloid polypeptide

Gene Summary

Predicted to enable identical protein binding activity. Involved in adenylate cyclase-activating G protein-coupled receptor signaling pathway; amylin receptor signaling pathway; and eating behavior. Predicted to be located in inclusion body and neuronal cell body. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in type 1 diabetes mellitus and type 2 diabetes mellitus. Orthologous to human IAPP (islet amyloid polypeptide). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • islet amyloid polypeptide
  • DAP
  • amylin
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Properties