Protein Name GATA binding protein 4
Organism Rattus norvegicus
Gene ID 54254
Gene Symbol

Gata4

UniProt P46152 (GATA4_RAT)
Relationships Total Number of functionally related compound(s) : 98
Total Number of Articles : 105
Description

GATA binding protein 4

Gene Summary

Enables several functions, including DNA-binding transcription factor activity, RNA polymerase II-specific; NFAT protein binding activity; and cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including cell growth involved in cardiac muscle cell development; positive regulation of BMP signaling pathway; and transdifferentiation. Located in nucleus. Used to study myocardial infarction. Biomarker of congenital heart disease and pulmonary hypertension. Human ortholog(s) of this gene implicated in congenital heart disease (multiple). Orthologous to human GATA4 (GATA binding protein 4). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • transcription factor GATA-4
  • DNA-binding protein GATA-GT2
  • GATA-binding factor 4
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Properties