Protein Name acyl-CoA synthetase long chain family member 1
Organism Homo sapiens
Gene ID 2180
Gene Symbol


UniProt P33121 (ACSL1_HUMAN), B7Z3Z9 (B7Z3Z9_HUMAN), B4E0R0 (B4E0R0_HUMAN), A8K9T3 (A8K9T3_HUMAN), E7EPM6 (E7EPM6_HUMAN)
Relationships Total Number of functionally related compound(s) : 80
Total Number of Articles : 83

acyl-CoA synthetase long chain family member 1

Gene Summary

The protein encoded by this gene is an isozyme of the long-chain fatty-acid-coenzyme A ligase family. Although differing in substrate specificity, subcellular localization, and tissue distribution, all isozymes of this family convert free long-chain fatty acids into fatty acyl-CoA esters, and thereby play a key role in lipid biosynthesis and fatty acid degradation. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2013]

  • long-chain-fatty-acid--CoA ligase 1
  • LACS 1
  • LACS 2
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