Protein Name glutathione reductase
Organism Danio rerio
Gene ID 553575
Gene Symbol

gsr

UniProt Q503Y5 (Q503Y5_DANRE), E7FGA5 (E7FGA5_DANRE)
Relationships Total Number of functionally related compound(s) : 10
Total Number of Articles : 8
Description

glutathione reductase

Gene Summary

Predicted to enable flavin adenine dinucleotide binding activity and glutathione-disulfide reductase (NADPH) activity. Acts upstream of or within cell redox homeostasis. Predicted to be located in cytoplasm. Predicted to be active in cytosol and mitochondrion. Is expressed in intestinal bulb; liver; and macrophage. Human ortholog(s) of this gene implicated in cataract; congenital nonspherocytic hemolytic anemia 10; and macular degeneration. Orthologous to human GSR (glutathione-disulfide reductase). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • glutathione reductase, mitochondrial
  • zgc:110010
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Properties