Protein Name DnaJ heat shock protein family (Hsp40) member B1
Organism Homo sapiens
Gene ID 3337
Gene Symbol

DNAJB1

UniProt P25685 (DNJB1_HUMAN), Q6FHS4 (Q6FHS4_HUMAN)
Relationships Total Number of functionally related compound(s) : 38
Total Number of Articles : 38
Description

DnaJ heat shock protein family (Hsp40) member B1

Gene Summary

This gene encodes a member of the DnaJ or Hsp40 (heat shock protein 40 kD) family of proteins. DNAJ family members are characterized by a highly conserved amino acid stretch called the 'J-domain' and function as one of the two major classes of molecular chaperones involved in a wide range of cellular events, such as protein folding and oligomeric protein complex assembly. The encoded protein is a molecular chaperone that stimulates the ATPase activity of Hsp70 heat-shock proteins in order to promote protein folding and prevent misfolded protein aggregation. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]

synonyms
  • dnaJ homolog subfamily B member 1
  • DnaJ (Hsp40) homolog, subfamily B, member 1
  • dnaJ protein homolog 1
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Properties