| Protein Name | granulin precursor |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 29143 |
| Gene Symbol | Grn |
| UniProt | P23785 (GRN_RAT), G3V8V1 (G3V8V1_RAT), Q6IN42 (Q6IN42_RAT), F1LMP7 (F1LMP7_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
34
Total Number of Articles : 25 |
Description |
granulin precursor |
| Gene Summary |
Predicted to enable protein-folding chaperone binding activity. Involved in several processes, including chondrocyte proliferation; positive regulation of dendritic spine development; and response to estradiol. Is active in glutamatergic synapse. Biomarker of status epilepticus. Human ortholog(s) of this gene implicated in dementia (multiple); neurodegenerative disease (multiple); neuronal ceroid lipofuscinosis 11; and primary progressive multiple sclerosis. Orthologous to human GRN (granulin precursor). [provided by Alliance of Genome Resources, Jul 2025] |
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