Protein Name anoctamin 6
Organism Homo sapiens
Gene ID 196527
Gene Symbol


UniProt Q4KMQ2 (ANO6_HUMAN), B3KX12 (B3KX12_HUMAN)
Relationships Total Number of functionally related compound(s) : 47
Total Number of Articles : 55

anoctamin 6

Gene Summary

This gene encodes a multi-pass transmembrane protein that belongs to the anoctamin family. This protein is an essential component for the calcium-dependent exposure of phosphatidylserine on the cell surface. The scrambling of phospholipid occurs in various biological systems, such as when blood platelets are activated, they expose phosphatidylserine to trigger the clotting system. Mutations in this gene are associated with Scott syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Mar 2011]

  • anoctamin-6
  • SCAN channel
  • small-conductance calcium-activated nonselective cation channel
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