Protein Name Rho guanine nucleotide exchange factor 1
Organism Homo sapiens
Gene ID 9138
Gene Symbol

ARHGEF1

UniProt Q92888 (ARHG1_HUMAN), A0A024R0R1 (A0A024R0R1_HUMAN)
Relationships Total Number of functionally related compound(s) : 43
Total Number of Articles : 48
Description

Rho guanine nucleotide exchange factor 1

Gene Summary

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined. [provided by RefSeq, Jul 2008]

synonyms
  • rho guanine nucleotide exchange factor 1
  • 115 kDa guanine nucleotide exchange factor
  • 115-kD protein
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Properties