Protein Name Kruppel-like transcription factor 5
Organism Mus musculus
Gene ID 12224
Gene Symbol

Klf5

UniProt Q9Z0Z7 (KLF5_MOUSE)
Relationships Total Number of functionally related compound(s) : 60
Total Number of Articles : 54
Description

Kruppel-like transcription factor 5

Gene Summary

Enables DNA-binding transcription factor activity, RNA polymerase II-specific; MRF binding activity; and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; regulation of DNA-templated transcription; and skeletal muscle tissue regeneration. Located in nucleus. Part of transcription regulator complex. Is expressed in several structures, including early conceptus; genitourinary system; gut; respiratory system; and sensory organ. Orthologous to human KLF5 (KLF transcription factor 5). [provided by Alliance of Genome Resources, Jul 2025]

synonyms
  • Krueppel-like factor 5
  • BTE-binding protein 2
  • Kruppel-like factor 5
Click to show/hide the synonyms
Properties