Protein Name CD40 ligand
Organism Homo sapiens
Gene ID 959
Gene Symbol

CD40LG

UniProt P29965 (CD40L_HUMAN)
Relationships Total Number of functionally related compound(s) : 407
Total Number of Articles : 515
Description

CD40 ligand

Gene Summary

The protein encoded by this gene is expressed on the surface of T cells. It regulates B cell function by engaging CD40 on the B cell surface. A defect in this gene results in an inability to undergo immunoglobulin class switch and is associated with hyper-IgM syndrome. [provided by RefSeq, Jul 2008]

synonyms
  • CD40 ligand
  • CD40 antigen ligand
  • CD40-L
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Properties