Protein Name estrogen receptor 2 (beta)
Organism Mus musculus
Gene ID 13983
Gene Symbol

Esr2

UniProt O08537 (ESR2_MOUSE), A0A1W2P736 (A0A1W2P736_MOUSE), A0A0R4J0Y6 (A0A0R4J0Y6_MOUSE)
Relationships Total Number of functionally related compound(s) : 211
Total Number of Articles : 390
Description

estrogen receptor 2 (beta)

Gene Summary

Enables DNA binding activity. Acts upstream of or within several processes, including hormone-mediated signaling pathway; nervous system development; and reproductive structure development. Located in cytoplasm and nucleus. Is expressed in several structures, including central nervous system; genitourinary system; heart mesentery; limb segment; and mammary gland primordium. Human ortholog(s) of this gene implicated in several diseases, including artery disease (multiple); autoimmune disease (multiple); hypospadias; neurodegenerative disease (multiple); and ovarian dysgenesis 8. Orthologous to human ESR2 (estrogen receptor 2). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • estrogen receptor beta
  • ER-beta
  • nuclear receptor subfamily 3 group A member 2
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Properties