Protein Name C-C motif chemokine ligand 11
Organism Mus musculus
Gene ID 20292
Gene Symbol

Ccl11

UniProt P48298 (CCL11_MOUSE)
Relationships Total Number of functionally related compound(s) : 154
Total Number of Articles : 164
Description

C-C motif chemokine ligand 11

Gene Summary

Predicted to enable CCR3 chemokine receptor binding activity; chemokine activity; and protein dimerization activity. Involved in several processes, including modulation of age-related behavioral decline; negative regulation of neurogenesis; and positive regulation of angiogenesis. Acts upstream of or within branching involved in mammary gland duct morphogenesis and mammary duct terminal end bud growth. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Is expressed in embryo; endocardial lining; liver parenchyma; liver vasculature; and yolk sac blood vessel. Human ortholog(s) of this gene implicated in asthma; human immunodeficiency virus infectious disease; hyperglycemia; and multiple sclerosis. Orthologous to several human genes including CCL11 (C-C motif chemokine ligand 11). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • eotaxin
  • C-C motif chemokine 11
  • chemokine (C-C motif) ligand 11
Click to show/hide the synonyms
Properties