Protein Name mucin 5B, oligomeric mucus/gel-forming
Organism Homo sapiens
Gene ID 727897
Gene Symbol

MUC5B

UniProt Q9HC84 (MUC5B_HUMAN)
Relationships Total Number of functionally related compound(s) : 255
Total Number of Articles : 234
Description

mucin 5B, oligomeric mucus/gel-forming

Gene Summary

This gene encodes a member of the mucin family of proteins, which are highly glycosylated macromolecular components of mucus secretions. This family member is the major gel-forming mucin in mucus. It is a major contributor to the lubricating and viscoelastic properties of whole saliva, normal lung mucus and cervical mucus. This gene has been found to be up-regulated in some human diseases, including sinus mucosa of chronic rhinosinusitis (CRS), CRS with nasal polyposis, chronic obstructive pulmonary disease (COPD) and H. pylori-associated gastric disease, and it may be involved in the pathogenesis of these diseases. [provided by RefSeq, Jul 2010]

synonyms
  • mucin-5B
  • cervical mucin MUC5B
  • high molecular weight salivary mucin MG1
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Properties