Protein Name caspase recruitment domain family member 14
Organism Homo sapiens
Gene ID 79092
Gene Symbol

CARD14

UniProt Q9BXL6 (CAR14_HUMAN)
Relationships Total Number of functionally related compound(s) : 24
Total Number of Articles : 20
Description

caspase recruitment domain family member 14

Gene Summary

This gene encodes a caspase recruitment domain-containing protein that is a member of the membrane-associated guanylate kinase (MAGUK) family of proteins. Members of this protein family are scaffold proteins that are involved in a diverse array of cellular processes including cellular adhesion, signal transduction and cell polarity control. This protein has been shown to specifically interact with BCL10, a protein known to function as a positive regulator of cell apoptosis and NF-kappaB activation. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Apr 2012]

synonyms
  • caspase recruitment domain-containing protein 14
  • CARD-containing MAGUK protein 2
  • bcl10-interacting maguk protein 2
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Properties