| Protein Name | nicotinamide phosphoribosyltransferase |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 297508 |
| Gene Symbol | Nampt |
| UniProt | Q80Z29 (NAMPT_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
85
Total Number of Articles : 93 |
Description |
nicotinamide phosphoribosyltransferase |
| Gene Summary |
Enables several functions, including cytokine activity; identical protein binding activity; and nicotinamide phosphoribosyltransferase activity. Involved in several processes, including cellular response to amyloid-beta; microglial cell activation; and negative regulation of cellular senescence. Predicted to be located in cell junction; cytoplasm; and nuclear speck. Predicted to be active in cytosol and mitochondrial matrix. Used to study middle cerebral artery infarction and transient cerebral ischemia. Biomarker of kidney failure; metabolic dysfunction-associated steatotic liver disease; periodontitis; and pulmonary hypertension. Human ortholog(s) of this gene implicated in transient cerebral ischemia. Orthologous to human NAMPT (nicotinamide phosphoribosyltransferase). [provided by Alliance of Genome Resources, Jul 2025] |
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| Properties | |