Protein Name nicotinamide phosphoribosyltransferase
Organism Rattus norvegicus
Gene ID 297508
Gene Symbol

Nampt

UniProt Q80Z29 (NAMPT_RAT)
Relationships Total Number of functionally related compound(s) : 85
Total Number of Articles : 93
Description

nicotinamide phosphoribosyltransferase

Gene Summary

Enables several functions, including cytokine activity; identical protein binding activity; and nicotinamide phosphoribosyltransferase activity. Involved in several processes, including cellular response to amyloid-beta; cellular response to oxygen-glucose deprivation; and negative regulation of cellular senescence. Located in cytoplasm; nucleus; and plasma membrane. Used to study middle cerebral artery infarction and transient cerebral ischemia. Biomarker of kidney failure; periodontitis; and pulmonary hypertension. Human ortholog(s) of this gene implicated in transient cerebral ischemia. Orthologous to human NAMPT (nicotinamide phosphoribosyltransferase). [provided by Alliance of Genome Resources, Apr 2022]

synonyms
  • nicotinamide phosphoribosyltransferase
  • NAmPRTase
  • pre-B-cell colony enhancing factor 1
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Properties