| Protein Name | cyclin D1 |
|---|---|
| Organism | Rattus norvegicus |
| Gene ID | 58919 |
| Gene Symbol | Ccnd1 |
| UniProt | P39948 (CCND1_RAT) |
| Relationships |
Total Number of functionally related compound(s) :
397
Total Number of Articles : 497 |
Description |
cyclin D1 |
| Gene Summary |
Enables protein kinase binding activity. Involved in several processes, including Leydig cell differentiation; response to corticosterone; and response to vitamin E. Predicted to be located in bicellular tight junction and nucleoplasm. Predicted to be part of cyclin D1-CDK4 complex; cyclin D1-CDK6 complex; and transcription repressor complex. Predicted to be active in cytoplasm; microtubule organizing center; and nucleus. Used to study prostate cancer and status epilepticus. Biomarker of atherosclerosis; impotence; interstitial cystitis; liver cancer; and transitional cell carcinoma. Human ortholog(s) of this gene implicated in several diseases, including carcinoma (multiple); colorectal cancer; hematologic cancer (multiple); invasive lobular carcinoma; and von Hippel-Lindau disease. Orthologous to human CCND1 (cyclin D1). [provided by Alliance of Genome Resources, Jul 2025] |
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