Protein Name oxysterol binding protein like 2
Organism Homo sapiens
Gene ID 9885
Gene Symbol

OSBPL2

UniProt Q9H1P3 (OSBL2_HUMAN), E7ET92 (E7ET92_HUMAN), B4DKJ8 (B4DKJ8_HUMAN)
Relationships Total Number of functionally related compound(s) : 41
Total Number of Articles : 25
Description

oxysterol binding protein like 2

Gene Summary

This gene encodes a member of the oxysterol-binding protein (OSBP) family, a group of intracellular lipid receptors. Most members contain an N-terminal pleckstrin homology domain and a highly conserved C-terminal OSBP-like sterol-binding domain, although the encoded protein contains only the sterol-binding domain. In vitro studies have shown that the encoded protein can bind strongly to phosphatic acid and weakly to phosphatidylinositol 3-phosphate, but cannot bind to 25-hydroxycholesterol. The protein associates with the Golgi apparatus. Transcript variants encoding different isoforms have been described. [provided by RefSeq, Sep 2014]

synonyms
  • oxysterol-binding protein-related protein 2
  • OSBP-related protein 2
  • DFNA67
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Properties