Protein Name hydroxysteroid 11-beta dehydrogenase 1
Organism Mus musculus
Gene ID 15483
Gene Symbol


UniProt P50172 (DHI1_MOUSE), Q4JHD9 (Q4JHD9_MOUSE)
Relationships Total Number of functionally related compound(s) : 184
Total Number of Articles : 215

hydroxysteroid 11-beta dehydrogenase 1

Gene Summary

Enables 11-beta-hydroxysteroid dehydrogenase (NADP+) activity. Acts upstream of or within lung development. Predicted to be located in apical part of cell; nuclear membrane; and rough endoplasmic reticulum. Predicted to be integral component of endoplasmic reticulum membrane. Is expressed in several structures, including alimentary system; cardiovascular system; genitourinary system; nervous system; and sensory organ. Used to study cortisone reductase deficiency 2. Human ortholog(s) of this gene implicated in cortisone reductase deficiency; cortisone reductase deficiency 2; and obesity. Orthologous to human HSD11B1 (hydroxysteroid 11-beta dehydrogenase 1). [provided by Alliance of Genome Resources, Apr 2022]

  • 11-beta-hydroxysteroid dehydrogenase 1
  • 11-beta-HSD1
  • 11-beta-HSD1A/MCR
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