Protein Name mitotic arrest deficient 1 like 1
Organism Homo sapiens
Gene ID 8379
Gene Symbol

MAD1L1

UniProt Q9Y6D9 (MD1L1_HUMAN)
Relationships Total Number of functionally related compound(s) : 18
Total Number of Articles : 18
Description

mitotic arrest deficient 1 like 1

Gene Summary

MAD1L1 is a component of the mitotic spindle-assembly checkpoint that prevents the onset of anaphase until all chromosome are properly aligned at the metaphase plate. MAD1L1 functions as a homodimer and interacts with MAD2L1. MAD1L1 may play a role in cell cycle control and tumor suppression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

synonyms
  • mitotic spindle assembly checkpoint protein MAD1
  • MAD1 mitotic arrest deficient like 1
  • MAD1-like protein 1
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Properties